Virginie Brom
Roche (Switzerland)(CH)
Publications by Year
Research Areas
Phosphodiesterase function and regulation, Amino Acid Enzymes and Metabolism, Protein Kinase Regulation and GTPase Signaling, Alzheimer's disease research and treatments, Bipolar Disorder and Treatment
Most-Cited Works
- → Selective GlyT1 Inhibitors: Discovery of [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a Promising Novel Medicine To Treat Schizophrenia(2010)134 cited
- → Discovery of benzoylisoindolines as a novel class of potent, selective and orally active GlyT1 inhibitors(2010)17 cited
- → Discovery of Orally Available and Brain Penetrant AEP Inhibitors(2023)14 cited
- → 3-Amido-3-aryl-piperidines: A Novel Class of Potent, Selective, and Orally Active GlyT1 Inhibitors(2014)5 cited