Josef R. Bencsik
Array BioPharma (United States)(US)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Synthesis and Biological Evaluation, Biochemical and Molecular Research, Synthesis and Reactions of Organic Compounds, Protein Kinase Regulation and GTPase Signaling
Most-Cited Works
- → Discovery and Preclinical Pharmacology of a Selective ATP-Competitive Akt Inhibitor (GDC-0068) for the Treatment of Human Tumors(2012)184 cited
- → Discovery of pyrrolopyrimidine inhibitors of Akt(2010)55 cited
- → Discovery and SAR of spirochromane Akt inhibitors(2011)42 cited
- → Diversification of the Three-Component Coupling of 2-Aminoheterocycles, Aldehydes, and Isonitriles: Efficient Parallel Synthesis of a Diverse and Druglike Library of Imidazo- and Tetrahydroimidazo[1,2-a] Heterocycles(2007)40 cited
- → Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors(2010)37 cited
- → C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators(2014)15 cited
- → Efficient, Stereoselective Synthesis of Oxazolo[3,2-a]pyrazin-5-ones: Novel Bicyclic Lactam Scaffolds from the Bicyclocondensation of 3-Aza-1,5-ketoacids and Amino Alcohols(2003)14 cited
- → Enantioselective Synthesis of (−)-LL-C10037α from Benzoquinone(1999)12 cited
- → Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA(2011)10 cited
- → Efficient, Stereoselective Synthesis of Oxazolo[3,2‐a]pyrazin‐5‐ones: Novel Bicyclic Lactam Scaffolds from the Bicyclocondensation of 3‐Aza‐1,5‐ketoacids and Amino Alcohols.(2003)2 cited