Efrat Finkin-Groner
Tri-Institutional Therapeutics Discovery Institute(US)
Publications by Year
Research Areas
Cholinesterase and Neurodegenerative Diseases, Computational Drug Discovery Methods, Synthesis and biological activity, Cancer-related Molecular Pathways, Ubiquitin and proteasome pathways
Most-Cited Works
- → Reversible histone glycation is associated with disease-related changes in chromatin architecture(2019)183 cited
- → Carbamate Derivatives of Indolines as Cholinesterase Inhibitors and Antioxidants for the Treatment of Alzheimer’s Disease(2012)75 cited
- → Synthesis and Biological Evaluation of Derivatives of Indoline as Highly Potent Antioxidant and Anti-inflammatory Agents(2018)58 cited
- → Structure of the human UBR5 E3 ubiquitin ligase(2023)38 cited
- → Synthesis and in vitro evaluation of anti-inflammatory activity of ester and amine derivatives of indoline in RAW 264.7 and peritoneal macrophages(2014)26 cited
- → Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates(2022)22 cited
- → Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10)(2021)22 cited
- → Deglycase-activity oriented screening to identify DJ-1 inhibitors(2021)21 cited
- → Indoline‐3‐propionate and 3‐aminopropyl carbamates reduce lung injury and pro‐inflammatory cytokines induced in mice by LPS(2014)21 cited
- → Dose-limiting inhibition of acetylcholinesterase by ladostigil results from the rapid formation and fast hydrolysis of the drug–enzyme complex formed by its major metabolite, R-MCPAI(2015)8 cited