John W. Ellingboe
Them (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Receptor Mechanisms and Signaling, Synthesis and biological activity, Hepatitis C virus research, Chemical Synthesis and Analysis
Most-Cited Works
- → Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin(2009)326 cited
- → Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease(2008)109 cited
- → Discovery of 5-Arylsulfonamido-3- (pyrrolidin-2-ylmethyl)-1H-indole Derivatives as Potent, Selective 5-HT6Receptor Agonists and Antagonists(2004)102 cited
- → Acylguanidines as Small-Molecule β-Secretase Inhibitors(2006)100 cited
- → Discovery of Pyrano[3,4-b]indoles as Potent and Selective HCV NS5B Polymerase Inhibitors(2004)97 cited
- → Discovery of Benzisoxazoles as Potent Inhibitors of Chaperone Heat Shock Protein 90(2008)94 cited
- → The Solid Phase Synthesis of Tri-Substituted Indoles(1997)85 cited
- → Aldol strategy: coordination of the lithium cation with an alkoxy substituent(1982)85 cited
- → Acylguanidine inhibitors of β-secretase: Optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets(2007)70 cited
- → Synthesis and Structure−Activity Relationship of N-Substituted 4-Arylsulfonylpiperidine-4-hydroxamic Acids as Novel, Orally Active Matrix Metalloproteinase Inhibitors for the Treatment of Osteoarthritis(2003)70 cited