Pui Yee Ng
Alkeus Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Lymphoma Diagnosis and Treatment, CAR-T cell therapy research, Sirtuins and Resveratrol in Medicine, Synthetic Organic Chemistry Methods, Asymmetric Synthesis and Catalysis
Most-Cited Works
- → Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes(2007)1,679 cited
- → AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer(2011)236 cited
- → Crystallographic structure of a small molecule SIRT1 activator-enzyme complex(2015)198 cited
- → Strained Silacycles in Organic Synthesis: A New Reagent for the Enantioselective Allylation of Aldehydes(2002)177 cited
- → Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma(2015)125 cited
- → Discovery of Imidazo[1,2- b ]thiazole Derivatives as Novel SIRT1 Activators(2009)117 cited
- → Discovery of oxazolo[4,5-b]pyridines and related heterocyclic analogs as novel SIRT1 activators(2008)90 cited
- → Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitors(2013)87 cited
- → REDUCTION OF ENDOTHELIAL AND SMOOTH MUSCLE DENSITY IN THE CORPORA CAVERNOSA OF THE STREPTOZOTOCIN INDUCED DIABETIC RAT(2000)83 cited
- → SIRT1 Modulation as a Novel Approach to the Treatment of Diseases of Aging(2010)75 cited