Timothy D. Gross
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Synthesis and Biological Evaluation, Synthesis and Reactivity of Heterocycles, Hypothalamic control of reproductive hormones, Receptor Mechanisms and Signaling
Most-Cited Works
- → (2,4,6-Triisopropylphenyl)selenium Bromide (TIPPSe-Br). An in Situ-Generated Reagent for Effecting Highly Selective Ring Closures of Homoallylic Alcohols to Substituted Tetrahydrofurans(1995)54 cited
- → 3-[(2R)-Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)- 6-methylpyrimidin-2,4-dione (NBI 42902) as a Potent and Orally Active Antagonist of the Human Gonadotropin-Releasing Hormone Receptor. Design, Synthesis, and in Vitro and in Vivo Characterization(2005)53 cited
- → Synthesis and Structure−Activity Relationships of 1-Arylmethyl-5-aryl-6-methyluracils as Potent Gonadotropin-Releasing Hormone Receptor Antagonists(2004)44 cited
- → A novel synthesis of 7-aryl-8-fluoro-pyrrolo[1,2-a]pyrimid-4-ones as potent, stable GnRH receptor antagonists(2002)33 cited
- → Chemical Development of NBI-75043. Use of a Flow Reactor to Circumvent a Batch-Limited Metal−Halogen Exchange Reaction(2008)33 cited
- → Synthesis and initial structure–Activity relationships of a novel series of imidazolo[1,2-a]pyrimid-5-ones as potent GnRH receptor antagonists(2002)31 cited
- → Design and Structure−Activity Relationships of 2-Alkyl-3-aminomethyl-6-(3-methoxyphenyl)-7-methyl-8-(2-fluorobenzyl)imidazolo[1,2-a]pyrimid-5-ones as Potent GnRH Receptor Antagonists(2003)31 cited
- → 3-(2-Aminoalkyl)-1-(2,6-difluorobenzyl)-5- (2-fluoro-3-methoxyphenyl)-6-methyl- uracils as Orally Bioavailable Antagonists of the Human Gonadotropin Releasing Hormone Receptor(2004)29 cited
- → An Approach to Early-Phase Salt Selection: Application to NBI-75043(2007)28 cited
- → Initial Structure–Activity Relationship Studies of a Novel Series of Pyrrolo[1,2-a]pyrimid-7-ones as GnRH Receptor Antagonists(2002)28 cited