Rajagopal V. Sekhar

Publications by Year

Research Areas

HIV-related health complications and treatments, HIV Research and Treatment, Folate and B Vitamins Research, Sulfur Compounds in Biology, Diabetes, Cardiovascular Risks, and Lipoproteins

Most-Cited Works

• → Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine(2010)398 cited
• → Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation(2011)322 cited
• → Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial(2021)156 cited
• → Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial(2022)134 cited
• → Metabolic basis of HIV-lipodystrophy syndrome(2002)120 cited
• → Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione(2013)99 cited
• → Severe Glutathione Deficiency, Oxidative Stress and Oxidant Damage in Adults Hospitalized with COVID-19: Implications for GlyNAC (Glycine and N-Acetylcysteine) Supplementation(2021)89 cited
• → GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage(2022)78 cited
• → HIV-1 Vpr Induces Adipose Dysfunction in Vivo Through Reciprocal Effects on PPAR/GR Co-Regulation(2013)77 cited
• → Pathophysiology of dyslipidemia and increased cardiovascular risk in HIV lipodystrophy: a model of ‘systemic steatosis’(2004)72 cited