Tatos Akopian
Harvard University(US)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Biochemical and Molecular Research, Tuberculosis Research and Epidemiology, Peptidase Inhibition and Analysis, RNA and protein synthesis mechanisms
Most-Cited Works
- → The Sizes of Peptides Generated from Protein by Mammalian 26 and 20 S Proteasomes(1999)576 cited
- → Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2(2014)426 cited
- → Lactacystin and clasto-Lactacystin β-Lactone Modify Multiple Proteasome β-Subunits and Inhibit Intracellular Protein Degradation and Major Histocompatibility Complex Class I Antigen Presentation(1997)382 cited
- → Proteasome Active Sites Allosterically Regulate Each Other, Suggesting a Cyclical Bite-Chew Mechanism for Protein Breakdown(1999)290 cited
- → Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide(1997)266 cited
- → Range of Sizes of Peptide Products Generated during Degradation of Different Proteins by Archaeal Proteasomes(1998)213 cited
- → Mycobacterium tuberculosis ClpP1 and ClpP2 Function Together in Protein Degradation and Are Required for Viability in vitro and During Infection(2012)201 cited
- → Processive Degradation of Proteins and Other Catalytic Properties of the Proteasome from Thermoplasma acidophilum(1997)200 cited
- → The Cyclic Peptide Ecumicin Targeting ClpC1 Is Active against Mycobacterium tuberculosis In Vivo(2014)188 cited
- → Structure-Based Design of Estrogen Receptor-β Selective Ligands(2004)175 cited