Xiaolun Wang
Mirati Therapeutics (United States)(US)
Publications by Year
Research Areas
Protein Kinase Regulation and GTPase Signaling, Melanoma and MAPK Pathways, Asymmetric Synthesis and Catalysis, Synthetic Organic Chemistry Methods, Synthesis and Catalytic Reactions
Most-Cited Works
- → Identification of MRTX1133, a Noncovalent, Potent, and Selective KRAS G12D Inhibitor(2021)661 cited
- → Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor(2022)475 cited
- → Strained Silacycles in Organic Synthesis: A New Reagent for the Enantioselective Allylation of Aldehydes(2002)177 cited
- → Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP -Deleted Cancers(2022)140 cited
- → Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein–Protein Interaction(2022)88 cited
- → Conformation-Specific Effects of Raf Kinase Inhibitors(2012)47 cited
- → Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure(2017)43 cited
- → Strained silacycle-catalyzed asymmetric Diels–Alder cycloadditions: the first highly enantioselective silicon Lewis acid catalyst(2006)42 cited
- → Strained Silacycles in Organic Synthesis: The Tandem Aldol−Allylation Reaction(2002)37 cited
- → Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis(2020)36 cited