Martine Hamel
Publications by Year
Research Areas
DNA Repair Mechanisms, Hepatitis C virus research, PARP inhibition in cancer therapy, Cell death mechanisms and regulation, Receptor Mechanisms and Signaling
Most-Cited Works
- → Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: Tertiary amides(2004)101 cited
- → The C3a receptor antagonist SB 290157 has agonist activity(2005)92 cited
- → RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors(2021)85 cited
- → Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides(2004)76 cited
- → Identification of N,N-Disubstituted Phenylalanines as a Novel Class of Inhibitors of Hepatitis C NS5B Polymerase(2003)68 cited
- → Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ(2022)62 cited
- → The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14(2011)55 cited
- → Pharmacological Characterization of MK-7246, a Potent and Selective CRTH2 (Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type 2 Cells) Antagonist(2010)54 cited
- → Applying the pro-drug approach to afford highly bioavailable antagonists of P2Y14(2010)50 cited
- → Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases(2010)49 cited