Christy L. Thoma
Pfizer (United States)(US)
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, Synthesis and biological activity, Phenothiazines and Benzothiazines Synthesis and Activities, Antibiotic Resistance in Bacteria, Pneumocystis jirovecii pneumonia detection and treatment
Most-Cited Works
- → Pyridone Methylsulfone Hydroxamate LpxC Inhibitors for the Treatment of Serious Gram-Negative Infections(2012)97 cited
- → Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections(2011)97 cited
- → Isothiazoloquinolones with Enhanced Antistaphylococcal Activities against Multidrug-Resistant Strains: Effects of Structural Modifications at the 6-, 7-, and 8-Positions(2006)52 cited
- → Isothiazoloquinolones containing functionalized aromatic hydrocarbons at the 7-position: Synthesis and in vitro activity of a series of potent antibacterial agents with diminished cytotoxicity in human cells(2005)44 cited
- → Small molecule inhibitors of E. coli primase, a novel bacterial target(2007)44 cited
- → Dual Targeting of DNA Gyrase and Topoisomerase IV: Target Interactions of Heteroaryl Isothiazolones in Staphylococcus aureus(2007)30 cited
- → In Vitro and In Vivo Antibacterial Activities of Heteroaryl Isothiazolones against Resistant Gram-Positive Pathogens(2007)29 cited
- → Biological evaluation of isothiazoloquinolones containing aromatic heterocycles at the 7-position: In vitro activity of a series of potent antibacterial agents that are effective against methicillin-resistant Staphylococcus aureus(2005)25 cited