Ariamala Gopalsamy
AstraZeneca (Brazil)(BR)Medicina(PL)Molecular Oncology (United States)(US)
Publications by Year
Research Areas
Hepatitis C virus research, Chemical Synthesis and Analysis, HIV/AIDS drug development and treatment, Quinazolinone synthesis and applications, Synthesis and biological activity
Most-Cited Works
- → Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes(2015)191 cited
- → Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S )-2,2-Difluorocyclopropyl)((1 R ,5 S )-3-(2-((1-methyl-1 H -pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)(2018)170 cited
- → Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue(2017)134 cited
- → A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation(2009)125 cited
- → Discovery of Pyrano[3,4-b]indoles as Potent and Selective HCV NS5B Polymerase Inhibitors(2004)97 cited
- → Identification of pyrimidine derivatives as hSMG-1 inhibitors(2012)