Kenneth J. Shaw
Janssen (United States)(US)
Publications by Year
Research Areas
Blood Coagulation and Thrombosis Mechanisms, Coagulation, Bradykinin, Polyphosphates, and Angioedema, Atrial Fibrillation Management and Outcomes, Protease and Inhibitor Mechanisms, Hemophilia Treatment and Research
Most-Cited Works
- → Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome(2004)770 cited
- → Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy.(1995)557 cited
- → Cardiotrophin-1(1995)432 cited
- → Routes to mitomycins. Chirospecific synthesis of aziridinomitosenes(1985)139 cited
- → Design, synthesis, and in vitro biological activity of benzimidazole based factor Xa inhibitors(2000)104 cited
- → Discovery of XL413, a potent and selective CDC7 inhibitor(2012)90 cited
- → Human Cardiotrophin-1: Protein and Gene Structure, Biological and Binding Activities, and Chromosomal Localization(1996)86 cited
- → Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro- 6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylglycine (ZK-807834): A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor Xa(1998)63 cited
- → Synthesis and Anti-HCV Activities of 4′-Fluoro-2′-Substituted Uridine Triphosphates and Nucleotide Prodrugs: Discovery of 4′-Fluoro-2′-C-methyluridine 5′-Phosphoramidate Prodrug (AL-335) for the Treatment of Hepatitis C Infection(2019)47 cited
- → Thiophene-Anthranilamides as Highly Potent and Orally Available Factor Xa Inhibitors(2007)46 cited