Keith Eagen
Electric Propulsion Laboratory (United States)(US)
Publications by Year
Research Areas
Blood Coagulation and Thrombosis Mechanisms, Coagulation, Bradykinin, Polyphosphates, and Angioedema, Synthesis and Catalytic Reactions, Synthetic Organic Chemistry Methods, Atrial Fibrillation Management and Outcomes
Most-Cited Works
- → Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry(2000)201 cited
- → Design, Synthesis, and Activity of 2-Imidazol-1-ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors(2007)67 cited
- → Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro- 6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylglycine (ZK-807834): A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor Xa(1998)63 cited
- → Structure–Activity relationships of substituted benzothiophene-anthranilamide factor Xa inhibitors(2003)40 cited
- → Metabolism-Based Identification of a Potent Thrombin Receptor Antagonist(2006)39 cited
- → Design, Synthesis, and Activity of 2,6-Diphenoxypyridine-Derived Factor Xa Inhibitors(1999)37 cited
- → Heterotricyclic Himbacine Analogs as Potent, Orally Active Thrombin Receptor (Protease Activated Receptor-1) Antagonists(2007)35 cited
- → Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor(2015)33 cited
- → Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists(2016)32 cited
- → Discovery and synthesis of a novel series of quinoline-based thrombin receptor (PAR-1) antagonists(2005)23 cited