Mekala Gunaratnam
Medway School of Pharmacy(GB)University College London(GB)
Publications by Year
Research Areas
DNA and Nucleic Acid Chemistry, Advanced biosensing and bioanalysis techniques, RNA Interference and Gene Delivery, Chromium effects and bioremediation, Heavy Metal Exposure and Toxicity
Most-Cited Works
- → Stabilization of G-Quadruplex DNA by Highly Selective Ligands via Click Chemistry(2006)227 cited
- → Molecular Basis of Structure–Activity Relationships between Salphen Metal Complexes and Human Telomeric DNA Quadruplexes(2011)218 cited
- → Trisubstituted Acridines as G-quadruplex Telomere Targeting Agents. Effects of Extensions of the 3,6- and 9-Side Chains on Quadruplex Binding, Telomerase Activity, and Cell Proliferation(2005)201 cited
- → Structure-Based Design and Evaluation of Naphthalene Diimide G-Quadruplex Ligands As Telomere Targeting Agents in Pancreatic Cancer Cells(2013)183 cited
- → Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule(2018)156 cited
- → Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands(2008)143 cited
- → Mechanism of acridine-based telomerase inhibition and telomere shortening(2007)133 cited
- → Targeting Human Gastrointestinal Stromal Tumor Cells with a Quadruplex-Binding Small Molecule(2009)132 cited
- → A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer(2015)114 cited
- → Tetrasubstituted naphthalene diimide ligands with selectivity for telomeric G-quadruplexes and cancer cells(2010)108 cited