Serge Burner
Roche (Switzerland)(CH)
Publications by Year
Research Areas
Amino Acid Enzymes and Metabolism, Phosphodiesterase function and regulation, Neuroscience and Neuropharmacology Research, Protein Kinase Regulation and GTPase Signaling, Synthesis and pharmacology of benzodiazepine derivatives
Most-Cited Works
- → Selective GlyT1 Inhibitors: Discovery of [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a Promising Novel Medicine To Treat Schizophrenia(2010)134 cited
- → Discovery of benzoylisoindolines as a novel class of potent, selective and orally active GlyT1 inhibitors(2010)17 cited
- → A short and efficient synthesis of the NMDA glycine site antagonist: (3R,4R)-3-amino-1-hydroxy-4-methyl pyrrolidin-2-one (L-687,414)(2008)10 cited
- → Synthesis of 4,6-Dihydro-4-oxopyrido[2,1-a]isoindroles and 4,6-Dihydro-6-oxothieno[2',3',:3,4]pyrrolo[1,2-a]pyridines(1994)8 cited
- → 3-Amido-3-aryl-piperidines: A Novel Class of Potent, Selective, and Orally Active GlyT1 Inhibitors(2014)5 cited
- → Radiosynthesis of [5‐[11C]methanesulfonyl‐2‐((S)‐2,2,2‐trifluoro‐1‐methyl‐ethoxy)‐phenyl]‐[5‐(tetrahydro‐pyran‐4‐yl)‐1,3‐dihydro‐isoindol‐2‐yl]‐methanone ([11C]RO5013853), a novel PET tracer for the glycine transporter type I (GlyT1)(2011)5 cited
- → ChemInform Abstract: Synthesis of 4,6‐Dihydro‐4‐oxopyrido(2,1‐a)isoindoles and 4,6‐Dihydro‐ 6‐oxothieno(2′,3′:3,4)pyrrolo(1,2‐a)pyridines.(1994)