Michelle R. Garnsey
Pfizer (United States)(US)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Asymmetric Synthesis and Catalysis, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Natural Compound Pharmacology Studies
Most-Cited Works
- → Deaminative Reductive Cross-Electrophile Couplings of Alkylpyridinium Salts and Aryl Bromides(2019)165 cited
- → Transforming Benzylic Amines into Diarylmethanes: Cross-Couplings of Benzylic Pyridinium Salts via C–N Bond Activation(2018)127 cited
- → Discovery of the Potent and Selective M1 PAM-AgonistN-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects(2016)83 cited
- → Development of a Strategy for the Asymmetric Synthesis of Polycyclic Polyprenylated Acylphloroglucinols via N-Amino Cyclic Carbamate Hydrazones: Application to the Total Synthesis of (+)-Clusianone(2010)66 cited
- → Direct Carbon−Carbon Bond Formation via Soft Enolization: A Biomimetic Asymmetric Mannich Reaction of Phenylacetate Thioesters(2010)58 cited
- → Design and Synthesis of γ- and δ-Lactam M1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M1-Selective PAM with Weak Agonist Activity(2017)58 cited
- → Short Enantioselective Total Syntheses of Cheloviolenes A and B and Dendrillolide C via Convergent Fragment Coupling Using a Tertiary Carbon Radical(2017)53 cited
- → Asymmetric total synthesis of (+)- and (−)-clusianone and (+)- and (−)-clusianone methyl enol ether via ACC alkylation and evaluation of their anti-HIV activity(2011)47 cited
- → Highly Modular Synthesis of 1,2-Diketones via Multicomponent Coupling Reactions of Isocyanides as CO Equivalents(2019)46 cited
- → Design and optimization of selective azaindole amide M1 positive allosteric modulators(2015)44 cited