Celia Dominguez
CHDI Foundation(US)
Publications by Year
Research Areas
Genetic Neurodegenerative Diseases, Mitochondrial Function and Pathology, Neurological disorders and treatments, Chemical Synthesis and Analysis, Synthesis and Biological Evaluation
Most-Cited Works
- → MAP Kinase p38Inhibitors: Clinical Results and an Intimate Look at Their Interactions with p38α Protein(2005)220 cited
- → A Soluble Base for the Copper-Catalyzed Imidazole N-Arylations with Aryl Halides(2005)172 cited
- p38 MAP kinase inhibitors: many are made, but few are chosen.(2005)
- → Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington’s Disease(2013)147 cited
- → Structure-Based Design of Novel Class II c-Met Inhibitors: 1. Identification of Pyrazolone-Based Derivatives(2012)102 cited
- → Novel Vanilloid Receptor-1 Antagonists: 2. Structure−Activity Relationships of 4-Oxopyrimidines Leading to the Selection of a Clinical Candidate(2007)98 cited
- → Discovery of a Potent, Selective, and Orally Bioavailable c-Met Inhibitor: 1-(2-Hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458)(2008)94 cited
- → Design, Synthesis, and Biological Evaluation of Potent c-Met Inhibitors(2008)90 cited
- → A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington’s Disease(2014)88 cited
- → Pharmacokinetics of memantine in rats and mice(2011)85 cited