François Bischoff
Janssen (Belgium)(BE)
Publications by Year
Research Areas
Neuroscience and Neuropharmacology Research, Chemical Synthesis and Analysis, Alzheimer's disease research and treatments, Computational Drug Discovery Methods, Receptor Mechanisms and Signaling
Most-Cited Works
- → 2-Amino-3,4-dihydroquinazolines as Inhibitors of BACE-1 (β-Site APP Cleaving Enzyme): Use of Structure Based Design to Convert a Micromolar Hit into a Nanomolar Lead(2007)145 cited
- → JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist(2004)138 cited
- → [3H]R214127: A Novel High-Affinity Radioligand for the mGlu1 Receptor Reveals a Common Binding Site Shared by Multiple Allosteric Antagonists(2003)115 cited
- → Synthesis, Structure−Activity Relationship, and Receptor Pharmacology of a New Series of Quinoline Derivatives Acting as Selective, Noncompetitive mGlu1 Antagonists(2005)96 cited
- → New 2-substituted 1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine having highly active and potent central α2-antagonistic activity as potential antidepressants(2000)69 cited
- → Design and Synthesis of a Novel Series of Bicyclic Heterocycles As Potent γ-Secretase Modulators(2012)60 cited
- → Extracellular interface between APP and Nicastrin regulates Aβ length and response to γ‐secretase modulators(2019)53 cited
- → A Positron Emission Tomography Radioligand for the in Vivo Labeling of Metabotropic Glutamate 1 Receptor: (3-Ethyl-2-[11C]methyl-6-quinolinyl)(cis- 4-methoxycyclohexyl)methanone(2005)47 cited
- → Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists(2013)46 cited
- → Synthesis and biodistribution of [11C]R107474, a new radiolabeled α2-adrenoceptor antagonist(2006)45 cited