Sunil Koovakkat
Publications by Year
Research Areas
Blood Coagulation and Thrombosis Mechanisms, Coagulation, Bradykinin, Polyphosphates, and Angioedema, Protease and Inhibitor Mechanisms, Click Chemistry and Applications, Hemophilia Treatment and Research
Most-Cited Works
- → Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro- 6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylglycine (ZK-807834): A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor Xa(1998)63 cited
- → Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors(1998)55 cited
- → Synthesis, Characterization, and Structure−Activity Relationships of Amidine-Substituted (Bis)benzylidene-Cycloketone Olefin Isomers as Potent and Selective Factor Xa Inhibitors(1999)43 cited
- → Design, Synthesis, and Activity of 2,6-Diphenoxypyridine-Derived Factor Xa Inhibitors(1999)37 cited
- → Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin(1999)31 cited
- → Design, Synthesis, and Activity of a Novel Series of Factor Xa Inhibitors: Optimization of Arylamidine Groups(2002)20 cited
- → Design, synthesis, and in vitro biological activity of indole-based factor Xa inhibitors(2000)17 cited
- → The rational design of inhibitors of nitric oxide formation by inducible nitric oxide synthase(2007)7 cited
- → Estimation of thermodynamic stability and charge distribution for unknown molecules: Nitro derivatives of cubane(1991)4 cited
- → ChemInform Abstract: Design, Synthesis, and in Vitro Biological Activity of Indole‐Based Factor Xa Inhibitors.(2000)