Balu Balasubramanian
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, Chemical Synthesis and Analysis, Synthesis and Biological Evaluation, Synthesis and biological activity, Growth Hormone and Insulin-like Growth Factors
Most-Cited Works
- → Discovery of a 1H-Benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity(2005)134 cited
- → Sordaricin antifungal agents(2003)61 cited
- → Sordarin Oxazepine Derivatives as Potent Antifungal Agents(2002)56 cited
- → Imidazole moiety replacements in the 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one inhibitors of insulin-like growth factor receptor-1 (IGF-1R) to improve cytochrome P450 profile(2007)46 cited
- → Non-camptothecin topoisomerase I active compounds as potential anticancer agents(2000)44 cited
- → Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R)(2007)40 cited
- → A Synthesis of N-Bridged 5,6-Bicylic Pyridines via A Mild Cyclodehydration Using the Burgess Reagent and Discovery of A Novel Carbamylsulfonylation Reaction(2008)39 cited
- → Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β- d-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model(2004)36 cited
- → Discovery of a Fluoroindolo[2,3-a]carbazole Clinical Candidate with Broad Spectrum Antitumor Activity in Preclinical Tumor Models Superior to the Marketed Oncology Drug, CPT-11(2005)36 cited
- → Synthesis of Biologically Active Piperidine Metabolites of Clopidogrel: Determination of Structure and Analyte Development(2015)30 cited