ChiehYing Y. Chang
Bristol-Myers Squibb (United States)(US)
Publications by Year
Research Areas
Monoclonal and Polyclonal Antibodies Research, Computational Drug Discovery Methods, Glycosylation and Glycoproteins Research, Metabolism, Diabetes, and Cancer, Growth Hormone and Insulin-like Growth Factors
Most-Cited Works
- → Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple α-helical coiled-coil(1994)248 cited
- → Discovery of a 1H-Benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity(2005)134 cited
- → Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain(2015)115 cited
- → The X-ray structure of an anti-tumour antibody in complex with antigen(1995)92 cited
- → Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)(2019)87 cited
- → Structure and specificity of the anti-digoxinantibody 40–50(1995)60 cited
- → Identification of Imidazo[1,2-b]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors(2019)49 cited
- → Small Molecule Antagonist of Leukocyte Function Associated Antigen-1 (LFA-1): Structure−Activity Relationships Leading to the Identification of 6-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic Acid (BMS-688521)(2010)43 cited
- → Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches(2020)43 cited
- → Discovery of an Oxybenzylglycine Based Peroxisome Proliferator Activated Receptor α Selective Agonist 2-((3-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic Acid (BMS-687453)(2010)40 cited