Janet Dell
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Protein Kinase Regulation and GTPase Signaling, Cancer-related Molecular Pathways, Virus-based gene therapy research, Growth Hormone and Insulin-like Growth Factors
Most-Cited Works
- → Discovery of a 1H-Benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity(2005)134 cited
- Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.(2002)
- → Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer(1999)109 cited
- → Structure−Activity Relationship of 3-Substituted N-(Pyridinylacetyl)-4- (8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)- piperidine Inhibitors of Farnesyl-Protein Transferase: Design and Synthesis of in Vivo Active Antitumor Compounds(1997)52 cited
- → Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events(2011)49 cited
- → Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice(1999)43 cited
- → Recombinant E1-Deleted Adenovirus-Mediated Gene Therapy for Cancer: Efficacy Studies with p53 Tumor Suppressor Gene and Liver Histology in Tumor Xenograft Models(1998)39 cited
- → Inhibitors of Farnesyl Protein Transferase. 4-Amido, 4-Carbamoyl, and 4-Carboxamido Derivatives of 1-(8-Chloro-6,11-dihydro-5H-benzo[5,6]- cyclohepta[1,2-b]pyridin-11-yl)piperazine and 1-(3-Bromo-8-chloro-6,11- dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperazine(1998)28 cited
- BMS-536924, a potent, small molecule inhibitor of the IGF-1 receptor in vitro and in vivo(2005)