Eric S. Marr
Publications by Year
Research Areas
HER2/EGFR in Cancer Research, Phosphodiesterase function and regulation, RNA and protein synthesis mechanisms, Cell Adhesion Molecules Research, Receptor Mechanisms and Signaling
Most-Cited Works
- → Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271(2008)380 cited
- → Spontaneous α-N-6-Phosphogluconoylation of a “His Tag” inEscherichia coli:The Cause of Extra Mass of 258 or 178 Da in Fusion Proteins(1999)215 cited
- → Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1 H -pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia†Coordinates of the PDE10A crystal structures have been deposited in the Protein Data Bank for compound 1 (3HQW), 2 (3HQY), 3 (3HQW) and 9 (3HR1).(2009)201 cited
- → Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains ofPseudomonas aeruginosa(2010)160 cited
- → Crystal structures of interleukin 17A and its complex with IL-17 receptor A(2013)141 cited
- → Discovery of a Series of 6,7-Dimethoxy-4-pyrrolidylquinazoline PDE10A Inhibitors(2006)112 cited
- → Theoretical and Experimental Design of Atypical Kinase Inhibitors: Application to p38 MAP Kinase(2005)79 cited
- → Synthesis and structure based optimization of novel Akt inhibitors(2008)75 cited
- → Identification of a Brain Penetrant PDE9A Inhibitor Utilizing Prospective Design and Chemical Enablement as a Rapid Lead Optimization Strategy(2009)65 cited
- → Pyridone-Conjugated Monobactam Antibiotics with Gram-Negative Activity(2013)63 cited