Hit-to-lead optimization of disubstituted oxadiazoles and tetrazoles as mGluR5 NAMs
Bioorganic & Medicinal Chemistry Letters2010Vol. 20(12), pp. 3737–3741
Citations Over TimeTop 18% of 2010 papers
Gábor Wágner, Csaba Wéber, O. Nyéki, Katalin Nógrádi, Attila Bielik, László Molnár, Amrita Bobok, Attila Horváth, Béla Kiss, Sándor Kolok, József Nagy, Dalma Kurkó, Krisztina Gál, István Greiner, Zsolt Szombathelyi, György M. Keserű, György Domány
Related Papers
- → Fragment-based lead discovery: leads by design(2005)339 cited
- → Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency(2010)185 cited
- → The role of molecular size in ligand efficiency(2007)164 cited
- → Biophysical Limits of Protein–Ligand Binding(2012)84 cited
- → A Practical Use of Ligand Efficiency Indices Out of the Fragment-Based Approach: Ligand Efficiency-Guided Lead Identification of Soluble Epoxide Hydrolase Inhibitors(2010)72 cited